Hoʻohana mākou i nā kuki e hoʻomaikaʻi i kou ʻike.Ma ka hoʻomau ʻana i kēia pūnaewele, ʻae ʻoe i kā mākou hoʻohana ʻana i nā kuki.ʻIke hou aku.
ʻO Halloysite nanotubes (HNT) he mau nanotubes pālolo e hiki ke hoʻohana ʻia i nā mea holomua ma muli o ko lākou ʻano hollow tubular kū hoʻokahi, biodegradability, a me nā waiwai mechanical a me ka ʻili.Eia naʻe, paʻakikī ka hoʻonohonoho ʻana o kēia mau nanotubes lepo ma muli o ka nele o nā ala pololei.
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Ma keia mea, he 'atikala i paʻi 'ia i loko o ka puke pai ACS Applied Nanomaterials paipai i ka pono hoʻolālā no fabricating kauoha HNT hale.Ma ka hoʻomaloʻo ʻana i kā lākou hoʻopuehu wai me ka hoʻohana ʻana i kahi rotor magnetic, ua aligned nā nanotubes pālolo ma kahi substrate aniani.
Ke hoʻoheheʻe ʻia ka wai, ʻo ka hoʻoulu ʻana o ka GNT aqueous dispersion e hoʻoulu i nā ikaika shear ma nā nanotubes pālolo, e hoʻohālikelike iā lākou i ke ʻano o nā apo ulu.Ua noiʻi ʻia nā ʻano mea like ʻole e pili ana i ka hoʻohālike HNT, e like me ka HNT concentration, nanotube charge, maloʻo wela, ka nui rotor, a me ka nui droplet.
Ma waho aʻe o nā mea kino, ua hoʻohana ʻia ka scanning electron microscopy (SEM) a me ka polarizing light microscopy (POM) e aʻo i ka microscopic morphology a me ka birefringence o nā apo lāʻau HNT.
Hōʻike nā hopena i ka wā i ʻoi aku ka nui o ka HNT ma mua o 5 wt%, hiki i nā nanotubes pālolo ke hoʻohālikelike pono, a ʻoi aku ka nui o ka HNT ʻoi aku ka nui o ka ʻili a me ka mānoanoa o ke kumu HNT.
Eia kekahi, ua hoʻolalelale ke kumu HNT i ka hoʻopili ʻana a me ka hoʻonui ʻia ʻana o nā pūnaewele fibroblast (L929), i ʻike ʻia e ulu ana ma ka alignment nanotube pālolo e like me ka mīkini hoʻopili.No laila, ʻo ke ala maʻalahi a me ka wikiwiki o kēia manawa no ka hoʻohālikelike ʻana i ka HNT ma nā substrates paʻa hiki ke hoʻomohala i kahi matrix pane-cell.
Hoʻokahi-dimensional (1D) nanoparticles e like me nā nanowires, nanotubes, nanofibers, nanorods a me nā nanoribbons ma muli o ko lākou kūlana mechanical, electronic, optical, thermal, biological and magnetic properties.
ʻO nā nanotubes Halloysite (HNTs) he mau nanotubes pālolo maoli me ke anawaena o waho o 50-70 nanometers a me ka lua o loko o 10-15 nanometers me ke ʻano Al2Si2O5(OH)4·nH2O.ʻO kekahi o nā hiʻohiʻona kūʻokoʻa o kēia mau nanotubes he mea ʻokoʻa o loko / waho kemika (aluminum oxide, Al2O3 / silicon dioxide, SiO2), e hiki ai i kā lākou hoʻololi koho.
Ma muli o ka biocompatibility a me ka haʻahaʻa haʻahaʻa loa, hiki ke hoʻohana ʻia kēia mau nanotubes pālolo i ka biomedical, nā mea hoʻonaninani a me nā noi mālama holoholona no ka mea he nanosafety maikaʻi loa nā nanotubes pālolo i nā moʻomeheu cell like ʻole.Loaʻa i kēia mau nanotubes pālolo nā mea maikaʻi o ke kumu kūʻai haʻahaʻa, ka loaʻa ākea, a me ka hoʻololi kemika maʻalahi o ka silane.
E pili ana ke kuhikuhi pili i ke ʻano o ka hoʻohuli ʻana i ka hoʻonohonoho cell ma muli o nā ʻano geometric e like me nā nano/micro grooves ma kahi substrate.Me ka hoʻomohala ʻana i ka ʻenekini kiko, ua hoʻohana nui ʻia ke ʻano o ka hoʻopili ʻana i ka morphology a me ka hoʻonohonoho ʻana o nā cell.Eia naʻe, ʻaʻole maopopo ke kaʻina olaola o ka hoʻomalu ʻana.
Hōʻike ka hana i kēia manawa i kahi kaʻina hana maʻalahi o ka hoʻokumu ʻana i ke apo ulu ulu HNT.Ma kēia kaʻina hana, ma hope o ka hoʻopili ʻana i kahi kulu o ka hoʻopuehu HNT i kahi paheʻe aniani poepoe, hoʻokomo ʻia ka hāʻule HNT ma waena o ʻelua mau wahi hoʻopili (ka paheʻe a me ka rotor magnetic) e lilo i mea hoʻopuehu e hele ai ma ka capillary.Mālama ʻia ka hana a maʻalahi.ka hoʻoheheʻe ʻia o nā mea hoʻoheheʻe hou aʻe ma ka lihi o ka capillary.
Ma ʻaneʻi, ʻo ka ikaika shear i hana ʻia e ka rotating magnetic rotating e hoʻokau i ka HNT ma ka lihi o ka capillary e waiho ma ka ʻili hoʻoheheʻe ma ke ala pololei.Ke hoʻoheheʻe ʻia ka wai, ʻoi aku ka ikaika o ka pilina ma mua o ka ikaika pinning, e koi ana i ka laina pili i ke kikowaena.No laila, ma lalo o ka hopena synergistic o ka ikaika shear a me ka ikaika capillary, ma hope o ka hoʻoheheʻe piha ʻana o ka wai, ua hoʻokumu ʻia kahi kumulāʻau kumulāʻau o HNT.
Eia hou, hōʻike nā hualoaʻa POM i ka birefringence ʻikea o ka hanana HNT anisotropic, kahi i hoʻohālikelike ʻia e nā kiʻi SEM i ka hoʻohālikelike like ʻana o nā nanotubes pālolo.
Eia hou, ua loiloi ʻia nā pūnaewele L929 i hoʻolaʻa ʻia ma nā nanotubes pālolo makahiki me nā ʻokoʻa like ʻole o ka HNT ma muli o kahi mīkini hoʻopili.ʻOiai, ua hōʻike nā pūnaewele L929 i ka hoʻohele like ʻole ma nā nanotubes lepo ma ke ʻano o nā apo ulu me 0.5 wt.% HNT.I loko o nā hale o ka pālolo nanotubes me ka NTG kaʻina o 5 a me 10 wt%, elongated cell i loaʻa ma ka aoao o ka lepo nanotubes.
I ka hopena, ua hana ʻia nā hoʻolālā apo ulu HNT macroscale me ka hoʻohana ʻana i kahi ʻano kumu kūʻai kūpono a me ka ʻenehana hou e hoʻonohonoho i nā nanoparticles i kahi ʻano hoʻonohonoho.ʻO ka hoʻokumu ʻana o ke ʻano o nā nanotubes pālolo e hoʻopili nui ʻia e ka HNT hoʻopaʻa ʻana, ka mahana, ka uku o ka ʻili, ka nui o ka rotor, a me ka nui droplet.Hāʻawi ka HNT i ka 5 a hiki i ka 10 wt.% i nā ʻāpana nanotubes lepo i kauoha nui ʻia, ʻoiai ma 5 wt.% ua hōʻike kēia mau ʻāpana i ka birefringence me nā kala ʻālohilohi.
Ua hōʻoia ʻia ka hoʻonohonoho ʻana o nā nanotubes pālolo ma ke ala o ka ikaika shear me ka hoʻohana ʻana i nā kiʻi SEM.Me ka hoʻonui ʻana i ka manaʻo o ka NTT, hoʻonui ka mānoanoa a me ka paʻakikī o ka uhi NTG.No laila, ke hāpai nei ka hana i kēia manawa i kahi ala maʻalahi no ke kūkulu ʻana i nā hale mai nā nanoparticles ma luna o nā wahi nui.
Chen Yu, Wu F, He Yu, Feng Yu, Liu M (2022).Hoʻohana ʻia kahi ʻano o "nā apo lāʻau" o nā nanotubes halloysite i hōʻuluʻulu ʻia e ka hoʻonāukiuki e hoʻomalu i ka alignment cell.Hoʻohana ʻia nā nanomaterials ACS.https://pubs.acs.org/doi/full/10.1021/acsanm.2c03255
Hoʻokaʻawale: ʻO nā manaʻo i hōʻike ʻia ma aneʻi ʻo ia ka manaʻo o ka mea kākau ma kona ʻano pilikino a ʻaʻole pono e hōʻike i nā manaʻo o AZoM.com Limited T/A AZoNetwork, ka mea nona a me ka mea hoʻokele o kēia pūnaewele.ʻO kēia ʻae ʻana he ʻāpana o nā ʻōlelo o ka hoʻohana ʻana i kēia pūnaewele.
He mea kākau ʻepekema ʻo Bhavna Kaveti mai Hyderabad, India.Loaʻa iā ia ka MSc a me MD mai ka Vellore Institute of Technology, India.i ke kemika lāʻau a me ka lāʻau lapaʻau mai ke Kulanui o Guanajuato, Mekiko.ʻO kāna hana noiʻi e pili ana i ka hoʻomohala ʻana a me ka synthesis o nā moleke bioactive e pili ana i nā heterocycles, a ua loaʻa iā ia ka ʻike ma ka multi-step and multi-component synthesis.I ka wā o kāna noiʻi kauka, ua hana ʻo ia i ka synthesis o nā ʻano molekole peptidomimetic heterocycle i hoʻopaʻa ʻia a hoʻohui ʻia i manaʻo ʻia e loaʻa i ka hiki ke hana hou i ka hana biological.ʻOiai ʻo ia e kākau ana i nā dissertation a me nā pepa noiʻi, ua ʻimi ʻo ia i kona makemake no ka kākau ʻepekema a me ka kamaʻilio.
Cavity, Buffner.(Sepatemaba 28, 2022).Hoʻouluʻia nā nanotubes Halloysite ma keʻano o "nā apo makahiki" ma keʻano maʻalahi.AZonano.Ua kiʻi ʻia ma ʻOkakopa 19, 2022 mai https://www.azonano.com/news.aspx?newsID=39733.
Cavity, Buffner."Hoʻoulu ʻia nā nanotubes Halloysite e like me nā 'apo makahiki' ma ke ʻano maʻalahi".AZonano.ʻOkakopa 19, 2022.ʻOkakopa 19, 2022.
Cavity, Buffner."Hoʻoulu ʻia nā nanotubes Halloysite e like me nā 'apo makahiki' ma ke ʻano maʻalahi".AZonano.https://www.azonano.com/news.aspx?newsID=39733.(Ma ʻOkakopa 19, 2022).
Cavity, Buffner.2022. Hoʻoulu ʻia nā nanotubes Halloysite i "nā apo makahiki" ma ke ʻano maʻalahi.AZoNano, loaʻa iā 19 ʻOkakopa 2022, https://www.azonano.com/news.aspx?newsID=39733.
Ma kēia nīnauele, kamaʻilio ʻo AZoNano iā Polofesa André Nel e pili ana i kahi noiʻi hou āna i komo ai e wehewehe ana i ka hoʻomohala ʻana o kahi nanocarrier "gā aniani" hiki ke kōkua i nā lāʻau lapaʻau e komo i nā pūnaewele maʻi pancreatic.
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